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KMID : 0357919790130020073
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Korean Journal of Pathology
1979 Volume.13 No. 2 p.73 ~ p.78
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Histopathological Study on Germ Cell Tumors of Hypothalamic Region -A Report of 5 Cases-
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서은주(徐恩珠)/Eun Joo Seo
이종재(李鐘哉)/송진언(宋鎭彦)/Chong Moo Lee/Jin Un Song
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Abstract
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Intracranial tumours histologically identical with seminoma or dysgerminoma of the
gonads have been called ectopic pinealoma, germinoma and atypical teratoma.
The origin of these tumors is difficult to explain. Primitive germ cells migrate over
wide areas of the embryo during early embryonic life. Very occasionally such germ cells
have been observed within the developing brain of the embryo.
We have experienced 5 cases of intracranial tumors which were confirmed
histopathologically as germinoma or teratoma during last 5 years at St. Mary Hospital,
Catholic Medical College.
The patients were between 12 and 23 years old. All of the cases were males except
one case of germinoma. The chief complaints of the male patients were nausea,
vomiting and visual disturbances, and histological diagnosis of these cases were 3
germinoma and 1 teratoma.
The female patient was 21 years old. The symptoms were those of diabetes inspidus
such as polydipaia and polyuria, nausea, vomiting, weight loss and amenorrhea of
several months duration. Histologically, it was proved as germinoina.
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